目的观察固本抑瘤Ⅱ号配合化学药物动脉灌注治疗原发性肝癌的疗效。方法将62例原发性肝癌患者随机分为治疗组(予固本抑瘤Ⅱ号配合化学药物动脉灌注)32例、对照组(予化学药物动脉灌注)30例,观察患者生活质量、化疗毒副反应,以及近、远期疗效。结果治疗组的稳定率为93.8%,1年生存率为78.1%、2年生存率为56.2%,都明显高于对照组。治疗组可缓解化疗药物的毒副反应,保护肝脏功能,改善患者的生活质量。结论固本抑瘤Ⅱ号有明显的减毒增效作用,固本抑瘤Ⅱ号配合化学药物动脉灌注治疗原发性肝癌有较好的疗效。 Objective To observe the curative effect of Gubenyiliu Ⅱ combined with chemical drug arterial infusion on primary liver cancer. Methods Sixty-two patients with primary hepatocellular carcinoma were randomly divided into treatment group (given Guben Decoction Ⅱ with chemical drug arterial infusion) in 32 cases and control group (given chemical drug arterial infusion) in 30 cases. The quality of life, Side effects, as well as near and long-term efficacy. Results The stability of the treatment group was 93.8%, the 1-year survival rate was 78.1%, and the 2-year survival rate was 56.2%, which were significantly higher than that of the control group. The treatment group can alleviate the side effects of chemotherapy drugs, protect the liver function and improve the quality of life of patients. Conclusion Gubenyixiang Ⅱ has obvious attenuation and synergic effects. Gubenyixin Ⅱ combined with chemical drugs arterial infusion has a good curative effect on primary liver cancer.