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目的：探讨角膜缘上皮联合羊膜移植治疗眼表疾病的临床效果．方法：对本院复发性翼状胬肉６例（６眼），睑球粘连３例（３眼），陈旧性碱烧伤３例（眼），角膜缘外伤２例（２眼），角巩膜大面积皮样囊肿１例（１眼），采用甘油保存的人羊膜联合自体或异体角膜缘移植进行治疗．结果：复发性翼状胬肉６例（６眼），术后随访４月～２年，上皮愈合稳定，角膜光滑透明，无１例复发．视力提高或保持不变．陈旧性碱烧伤３例（４眼），分别随访３、８、１２个月，眼表面保持安静，角膜中央无血管生长，周边部有少许的新生血管；１例手术失败，出现广泛的角膜血管生长，基质溶解．１例角巩膜大面积皮样囊肿，术后角膜半透明，外观正常，视力除１例失败外，视力均有不同程度提高，从术前光感－０．０５提高至０．０２｀０．８不等．结论：保存的人羊膜无抗原性，具有抗炎和抑制新生血管及纤维化、阻止结膜源组织再侵入的作用．用角膜缘上皮联合羊膜移植是一种有效的治疗眼表疾病的手段．
Objective: To investigate the clinical effect of corneal limbal epithelium combined with amniotic membrane transplantation for the treatment of ocular surface diseases. Methods: Six cases of recurrent pterygium (6 eyes), 3 cases of symblepharon (3 eyes), 3 cases of old alkali burns (eyes), 2 cases of limbal trauma (2 eyes), and sclera One case (1 eye) of dermoid cyst was treated with glycerin-preserved human amniotic membrane combined with autologous or allograft limbal transplantation. Results: Six cases (6 eyes) of recurrent pterygium were followed up for 4 months to 2 years. The epithelium healed well and the cornea was smooth and transparent without recurrence. Eyesight improved or remained unchanged. Three cases (4 eyes) of old alkali burns were followed up for 3, 8, and 12 months respectively. The surface of the eye remained quiet with no corneal neovascularization and a few neovascularization around the cornea. One case failed the operation and showed extensive corneal blood vessels Growth, matrix dissolution. One case of large scleral dermoid cysts, postoperative corneal translucency, the appearance of normal, except for 1 case of visual acuity failure, the visual acuity increased in varying degrees, from preoperative light sensitivity -0.05 to 0.02 `0. 8 range. Conclusion: The preserved human amniotic membrane has no antigenicity, anti-inflammatory and anti-angiogenic and fibrotic effects, prevent the invasion of conjunctival tissue again. Corneal limbal epithelium combined with amniotic membrane transplantation is an effective treatment of ocular surface disease means.