Amberlyst-15~ in PEG:A novel catalytic system for the facile and efficient one-pot synthesis of ben

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A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo-[2,3-b]-quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole, cyclic-diketones and various aldehydes using Amberlyst-15 in PEG 400 as an environmentally benign and reusable catalyst system. Environmental benignity, recyclability, cost-effectiveness, easy workup and excellent yields are the major attributes of this one-pot procedure. A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo- [2,3-b] -quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole, cyclic-diketones and various aldehydes using Amberlyst Environmental benignity, recyclability, cost-effectiveness, easy workup and excellent yields are the major attributes of this one-pot procedure.
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