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本文对36例儿童急性淋巴细胞白血病(急淋)的发热进行分析。患儿年龄22月～12岁,观察1周～38月,将体温在38℃以上持续至少4小时定为发热,并排除因药物和输血引起的发热反应。全部病例用长春新碱、强的松龙和加用左旋门冬酰胺酶作诱导缓解;缓解后进行颅脑照射和辅内注射氨甲喋呤来防治中枢神经系统白血病。结果:共发热117例次。一个患儿平均发热次数,诱导缓解期(每人每月平均发热1.2次)和复发期(0.8次)比中枢神经系统防治期(0.41次)和维持治疗期(0.15次)为多。117例次发热中仅有51％左右可肯定为
This article analyzes 36 children with acute lymphoblastic leukemia (emergency) fever. The patient’s age ranged from 22 months to 12 years. From 1 week to 38 months of observation, the body temperature was determined to be fever at 38°C or higher for at least 4 hours, and the fever reaction due to drugs and blood transfusion was excluded. All cases were treated with vincristine, prednisolone and added L-asparaginase for induction of remission; after remission, brain irradiation and intravitreal injection of methotrexate were used to prevent central nervous system leukemia. Results: A total of 117 cases of fever. The average number of fevers in one patient, induction remission (1.2 fever per person per month on average), and relapse (0.8 times) were greater than those in the central nervous system (0.41) and maintenance treatment (0.15). Only about 51% of the 117 cases of fever can be confirmed as