芳酰乙酸乙酯在乙氧基镁的作用下与取代的苯甲酰氯反应生成2-取代苯并吡喃酮。2-取代苯并吡喃酮和盐酸羟胺经Beckmann重排反应合成了4H-[1]苯并吡喃[3,4-d]异噁唑-4-酮。X衍射谱图表明,反应过程中表现区域选择性。对该反应的反应机理进行了初探。 Ethyl aroylacetate reacts with substituted benzoyl chloride under the action of ethoxymagnesium to form 2-substituted benzopyrone. 2H- [1] benzopyrano [3,4-d] isoxazol-4-one was synthesized by Beckmann rearrangement reaction between 2-substituted benzopyrone and hydroxylamine hydrochloride. The X-ray diffraction pattern shows that the reaction region exhibits region selectivity. The reaction mechanism of the reaction was explored.