论文部分内容阅读
本文报道了一类新的抗神经性毒剂化合物,对称的不含肟基的双吡啶季铵盐的合成.其中化合物A_4和A_7预防小鼠梭曼中毒的ED_(50)值分别为32和21.6mg/kg.
In this paper, we report the synthesis of a new class of anti-neurotoxic agents, the symmetric non-oxime-containing quaternary ammonium salts of pyridine, in which the ED 50 values of the compounds A 4 and A 7 in preventing soman intoxication were 32 and 21.6, respectively mg / kg.