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阿托品(atropine)属M胆碱受体阻断药,其作用机制为竞争性拮抗M胆碱受体。阿托品在临床上的应用有:解除平滑肌痉挛、制止腺体分泌、眼科、缓慢型心律失常、抗休克、解救有机磷酸酯类中毒和有些毒蕈类的中毒等。阿托品具有多种药理作用,临床上应用其中一种作用时,其他的作用则成为副作用。临床上青光眼及前列腺肥大患者忌用阿托品。阿托品的最低致死量成人为80mg～130mg,儿童约为10mg。阿托品中毒解救主要为对症治疗。
Atropine is a cholinergic receptor blocker that acts competitively against the M cholinergic receptor. Atropine in clinical application are: relieve smooth muscle spasm, to stop the secretion of glands, ophthalmology, bradyarrhythmia, anti-shock, rescue organophosphate poisoning and some poisoning mushroom poisoning. Atropine has a variety of pharmacological effects, clinical application of one of the role, the other side effects have become side effects. Clinical glaucoma and prostatic hypertrophy in patients with atropine. Atropine minimum lethal adult 80mg ~ 130mg, children about 10mg. Atropine poisoning rescue symptomatic treatment.