论文部分内容阅读
目的探讨他克莫司对老年激素抵抗型肾病综合征的治疗效果,以供参考。方法临床研究对象是我院2014年1月~2015年12月收治的老年激素抵抗型肾病综合征患者80例,随机分成A组和B组,均给予常规治疗。A组患者加环磷酰胺,B组患者加他克莫司。对比两组患者治疗前后白蛋白、24小时尿蛋白、总胆固醇的差异。结果两组患者治疗前白蛋白、24小时尿蛋白、总胆固醇差异无统计学意义(P>0.05)。治疗后B组白蛋白、24小时尿蛋白、总胆固醇优于A组(P<0.05)。结论他克莫司对老年激素抵抗型肾病综合征的治疗效果确切。
Objective To investigate the effect of tacrolimus on senile hormone-resistant nephrotic syndrome for reference. Methods The clinical study object was 80 patients with senile hormone-resistant nephrotic syndrome admitted from January 2014 to December 2015 in our hospital. Patients were randomly divided into A group and B group, and were given routine treatment. Patients in group A received cyclophosphamide, and patients in group B received tacrolimus. Before and after treatment, albumin, 24-hour urine protein and total cholesterol were compared between the two groups. Results There was no significant difference in albumin, 24-hour urine protein and total cholesterol between the two groups before treatment (P> 0.05). After treatment, albumin, 24-hour urine protein and total cholesterol in group B were better than those in group A (P <0.05). Conclusion Tacrolimus treatment of senile hormone-resistant nephrotic syndrome is effective.