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本文报告1970～1972年美国18所医院与34所临床诊所协作研究822例初治肺结核患者以异菸肼(INH)+利福平(RFP)(三种不同剂量)治疗的疗效与毒性,以及痰阴转后再以INH+乙胺丁醇(EMB)治疗12或18个月的疗效。计男性646例,女性176例。年令自20～64岁。病变属轻度13例,中度260例,重度549例。痰菌皆阳性。治疗分二阶段;第一阶段按RFP用量不同分三组;第一组INH0.3/日+RFP0.45/日(324例),第二组INH
This article reports the efficacy and toxicity of 1822 newly diagnosed tuberculosis patients treated with isoniazid (INH) + rifampin (RFP) (three different doses) in 18 U.S. hospitals and 34 clinical clinics from 1970 to 1972, and After sputum conversion to INH ethambutol (EMB) for 12 or 18 months of treatment. Total 646 males and 176 females. Year from 20 to 64 years old. Lesions were mild in 13 cases, moderate in 260 cases, severe in 549 cases. Phlegm are positive. Treatment divided into two phases; the first phase according to the amount of RFP divided into three groups; the first group of INH0.3 / day + RFP0.45 / day (324 cases), the second group of INH