论文部分内容阅读
目的总结急性呼吸窘迫综合征 ( ARDS)获得性肺部感染的致病菌和对抗生素的耐药情况。方法对 1993年 6月～ 1998年 3月收集的 ARDS获得性肺部感染 46例患者的痰菌检查和对抗生素的药物敏感结果进行分析。结果共培养出 6 5株细菌 ,其中革兰阴性杆菌占 76 .9% ,对 12种抗生素呈现不同程度的耐药 ,只有复达欣 ,丁胺卡那霉素和喹诺酮类敏感率在 6 0 %以上。革兰阳性球菌占2 3.1% ,头孢唑啉 ,丁胺卡那霉素和万古霉素对表皮葡萄球菌的敏感率为 70 % ,粪肠球菌除万古霉素的敏感率在 6 6 .7%外 ,对 12种抗生素都高度耐药。结论增强 ARDS患者的抵抗力 ,加强营养支持治疗 ,及时清理呼吸道分泌物 ,严格无菌操作 ,合理应用抗生素是减少获得性肺部感染 ,降低 ARDS患者病死率的重要措施
Objective To summarize the pathogens of acquired pulmonary infection and the resistance to antibiotics in acute respiratory distress syndrome (ARDS). Methods Thirty-six patients with ARDS-acquired pulmonary infections collected from June 1993 to March 1998 were tested for sputum and drug susceptibility to antibiotics. Results A total of 65 strains of bacteria were cultured, of which Gram-negative bacilli accounted for 76.9%, showing resistance to 12 antibiotics to varying degrees. Only the susceptibility rates of Fu-Daxin, amikacin and quinolones were 60% %the above. Gram positive cocci accounted for 23.1%, cefazolin, amikacin and vancomycin susceptibility of Staphylococcus epidermidis was 70%, E. faecalis vancomycin sensitivity rate of 6.67% In addition, the 12 kinds of antibiotics are highly resistant. CONCLUSIONS: It is an important measure to reduce the acquired pulmonary infection and reduce the mortality of patients with ARDS by enhancing the resistance of patients with ARDS, strengthening nutrition supportive treatment, clearing respiratory secretions in time and strictly aseptic operation.