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肺炎链球菌多糖疫苗(PPV)用于肺炎链球菌性疾病发病风险较高的2岁及以上儿童和成人预防肺炎链球菌性疾病。肺炎链球菌性疾病已经成为严重威胁人类健康的疾病之一,肺炎链球菌耐药性增加和耐药菌株的广泛传播,加大了肺炎链球菌性疾病的治疗难度,因此在高风险人群中推广接种肺炎链球菌疫苗具有重大的公共卫生意义。2012年中华预防医学会发布了《肺炎链球菌性疾病相关疫苗应用技术指南(2012版)》,将疫苗防治对象扩大到成人和老人。在我国,肺炎链球菌疫苗为第二类疫苗,尚未进入国家免疫规划,肺炎链球菌多糖疫苗在高风险成人中的应用才刚起步。本文就肺炎链球菌多糖疫苗在高风险成人中的应用现状进行综述,以供今后推进相关工作参考。
Streptococcus pneumoniae Polysaccharide Vaccine (PPV) is used in the prevention of pneumococcal disease in children and adults 2 years of age and older at a high risk of developing a pneumococcal disease. Streptococcus pneumoniae disease has become a serious threat to human health, one of the diseases, Streptococcus pneumoniae increased resistance and the spread of drug-resistant strains, increased the difficulty of treatment of pneumococcal disease, so the promotion of high-risk groups Vaccination with pneumococcal vaccine has a significant public health significance. In 2012, Chinese Preventive Medicine Society released the “Technical Guide for the Application of Vaccine against Streptococcus pneumoniae Disease (Version 2012)” to extend the target of vaccine control to adults and the elderly. In our country, pneumococcal vaccine is the second type of vaccine, has not yet entered the national immunization program, the application of pneumococcal polysaccharide vaccine in high-risk adults just started. This review summarizes the status quo of application of Streptococcus pneumoniae polysaccharide vaccine in high-risk adults for future reference.