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用~(131)Ⅰ标记抗人肝癌铁蛋白抗体对16例原发性肝癌患者作放射免疫显像分析。结果:显像阳性率为81.3%,其中经肝动脉插管和经外周静脉注射者各8例,前者阳性率为100%,注射后当天用单光子发射计算机处理断层摄影即可获得阳性显像,以第4~6天显像最为清晰,有3例追踪到第20天仍可获阳性显像。后者阳性率为62.5%,以第5~7天显像最为清晰。第3、5和8天肝癌与周围肝组织的中位放射强度比值前者分别为1.4,1.6和1.8,最高可达2.9;后者分别为1.2、1.3和1.4最高达1.8。
Radioimmunoscintigraphy of 16 cases of primary liver cancer were performed with ~ (131) I-labeled anti-human hepatic carcinoma protein. RESULTS: The positive rate of imaging was 81.3%. Among them, 8 cases were treated with hepatic artery catheterization and 8 cases by peripheral vein injection. The positive rate of the former was 100%. After the injection, a single photon emission computer was used to process the tomography to obtain positive imaging. The 4th to 6th days were the most clear images, and 3 cases still had positive images on the 20th day. The latter positive rate was 62.5%, with the sharpest image on the 5th to 7th day. The ratios of median radiation intensity of liver cancer and surrounding liver tissue on the 3rd, 5th and 8th days were 1.4, 1.6 and 1.8, respectively, with the highest being 2.9; the latter being 1.2, 1.3 and 1.4 up to 1.8, respectively.