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目的探讨综合治疗对妊娠期糖尿病(GDM)患者的临床影响。方法选择门诊80例GDM患者,随机分为观察组和对照组,每组40例。对照组采用常规治疗,观察组在对照组的基础上给予个性化饮食指导和健康教育等综合治疗,观察两组治疗前后空腹血糖(FPG)、糖化血红蛋白(HbA1c)变化和围生期母婴情况。结果治疗前两组FPG、HbA1c差异无统计学意义(P>0.05),治疗后观察组FPG、HbA1c显著低于对照组(P<0.05)。围生期观察组剖宫产、胎膜早破、胎儿宫内窘迫、巨大儿等发生率明显低于对照组(P<0.05);观察组新生儿低血糖发生率明显低于对照组(P<0.05),而5 minApgar评分显著高于对照组(P<0.05)。结论综合治疗能有效控制GDM患者病情,改善妊娠结局。
Objective To investigate the clinical effect of comprehensive treatment on gestational diabetes mellitus (GDM). Methods 80 cases of outpatients with GDM were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with conventional therapy. The observation group was given comprehensive diet guidance and health education on the basis of the control group. The changes of fasting blood glucose (FPG), HbA1c and perinatal mothers and infants were observed before and after treatment . Results There was no significant difference in FPG and HbA1c between the two groups before treatment (P> 0.05). After treatment, the FPG and HbA1c in the observation group were significantly lower than those in the control group (P <0.05). The incidence of cesarean section, premature rupture of membranes, fetal distress and macrosomia in perinatal observation group was significantly lower than that in control group (P <0.05). The incidence of neonatal hypoglycemia in observation group was significantly lower than that in control group (P <0.05), while the 5 minApgar score was significantly higher than that of the control group (P <0.05). Conclusion The comprehensive treatment can effectively control the condition of GDM patients and improve the pregnancy outcome.