肾病综合征出血热(HFRS)继续严重威胁着人类的健康。作者报道了某些HFRS和相关病毒之间的抗原和基因关系。以往汉坦病毒(Hantaan病毒,以下简称HTN病毒)的基因组分析与形态学观察一致,发现HTN病毒最接近布尼雅病毒科(Bunyaviridae)中的病毒,符合该科病毒的所有必备分类标准。可是,在HTN病毒和布尼雅病毒科的某些病毒之间,没有易证实的血清学关系以及各自独特的遗传学和流行病学特征,不利于确定属的分类。有意义的是通过免疫荧光测定发现,最近从地方性流行区以及未见 Hemorrhagic fever with nephrotic syndrome (HFRS) continues to be a serious threat to human health. The authors report on the antigenic and genetic relationships between certain HFRS and related viruses. In the past, genomic analysis of the Hantaan virus (HTN) was consistent with morphological observations and found that the HTN virus was closest to the virus in the Bunyaviridae family and met all the essential classification criteria for this family of viruses. However, there is no readily identifiable serological relationship between HTN and certain viruses in the Bunyaviridae and their respective genetic and epidemiological characteristics, which is detrimental to the classification of genera. What makes sense is found by immunofluorescence, recently seen from endemic areas and not seen