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目的总结河南宏力医院抗菌药物专项整治的效果,为下一步专项整治活动的深入进行提供依据。方法通过对医院2009年至2012年的抗菌药物销售额占药品销售总额的比例(使用比例)、每万元药品销售额的抗菌药物消耗量(累计DDD数)、各类抗菌药物的销售额及构成比、排名前十位的抗菌药物销售额及占抗菌药物销售总额的百分比这几个指标进行比较和分析。结果抗菌药物的使用比例从整治前的17.96%(2010年)降到11.61%(2012年),每万元药品销售额的抗菌药物消耗量(累计DDD数)从110.90(2009年)降到67.17(2012年),均呈逐年下降趋势;β-内酰胺类抗菌药物仍是使用比例最高的抗菌药物,用量占到全部抗菌药物使用总量的80%以上;氟喹诺酮类药物使用比例不高,但呈逐年上升趋势。结论医院抗菌药物专项整治活动取得了明显效果,抗菌药物的使用总体趋于合理,但氟喹诺酮类药物使用比例呈逐年上升趋势,应引起重视。
Objective To summarize the effect of special rectification of antimicrobial agents in Henan Grace Hospital and provide evidence for the further rectification activities. Methods According to the ratio of antimicrobial drug sales to the total drug sales (using ratio), antimicrobial drug consumption (cumulative DDD) of drug sales per million yuan, sales of various antimicrobial drugs and Composition ratio, the top ten sales of antibacterial drugs and antibacterial drugs accounted for the percentage of total sales of these indicators were compared and analyzed. As a result, the use of antibacterials dropped from 17.96% (2010) before remediation to 11.61% (2012), and the antimicrobial consumption per unit of drug sales (cumulative DDD) decreased from 110.90 (2009) to 67.17 (2012), showing a year by year decline; β-lactam antibiotics are still the highest proportion of the use of antibacterial drugs, the amount accounted for more than 80% of the total use of antibacterial drugs; fluoroquinolones use is not high, However, it has been increasing year by year. Conclusion The special rectification activities of antimicrobial agents in hospitals have achieved remarkable results. The use of antimicrobial agents has generally been rational. However, the proportion of fluoroquinolones used has been increasing year by year, which deserves our attention.