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目的探讨不同手术方法治疗梭型细胞分化的恶性潜能未定型子宫平滑肌肿瘤的术后复发情况。方法选取2009年1月1日至2015年12月30日期间在中国人民解放军陆军总医院妇科接受手术治疗,经病理科医师采用同一诊断标准对手术切片再次复核后证实患有梭型细胞分化的恶性潜能未定型子宫平滑肌肿瘤的患者。通过搜集临床资料及术后随访,比较不同手术方式和途径对术后复发率的影响。结果搜集到23位患者,随访时间2.5~69个月,2例(1例行经腹子宫肿物切除术治疗,1例行腹腔镜下子宫肿物切除术治疗)于术后复发。将子宫肿物切除术组和全子宫切除术组以及经腹手术组和腔镜手术组进行Fisher确切概率检验,双侧检验P值均大于0.05。结论尚不能认为采用不同手术方法(全子宫切除术、子宫肿物切除术)及手术途径(经腹、腔镜手术)治疗该肿瘤在术后复发率方面有显著差异,但仍需通过扩大样本量进一步证实。
Objective To investigate the postoperative recurrence of malignant latent untouched uterine smooth muscle tumors treated by different surgical methods for spindle cell differentiation. Methods The surgical treatment was performed in the gynecology department of the PLA General Hospital of PLA from January 1, 2009 to December 30, 2015. The same diagnostic criteria were applied to the gynecological department of the PLA General Hospital to confirm the presence of spindle cell differentiation Patients with malignant potential untypical uterine smooth muscle tumors. The clinical data and postoperative follow-up were collected to compare the effect of different surgical methods and approaches on postoperative recurrence rate. RESULTS: Twenty-three patients were followed up for 2.5- to 69-months. Two patients (1 underwent transabdominal hysterectomy and 1 underwent laparoscopic hysterectomy) experienced postoperative recurrence. Fisher exact test was performed on the hysterectomy group, the hysterectomy group, the transabdominal group and the endoscopic surgery group, and both P values were greater than 0.05. Conclusions It is not yet considered that there is a significant difference in the recurrence rate of the tumor treated with different surgical methods (hysterectomy, hysterectomy) and surgical approach (transabdominal and endoscopic surgery). However, Further confirmation.