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目的观察波立维联合参麦注射液治疗急性脑分水岭梗死的疗效。方法将48例急性脑分水岭梗死患者随机分为治疗组和对照组,两组均同时应用神经细胞活化剂胞二磷胆碱或脑蛋白水解物等,并根据患者血压情况给予纠正低血压、补充血容量及脑血管二级预防治疗。治疗组应用波立维75mg,口服,每日1次;参麦注射液50ml加入生理盐水250ml中,静脉滴注,每日1次。对照组应用波立维75mg口服,每日1次。两组均以7d为1个疗程。结果治疗组总有效率和显效率分别为92.3%、75%,对照组总有效率和显效率分别为80%、60%。两组比较差异有显著统计学意义(χ2=16.372,P<0.01)。结论波立维联合参麦注射液治疗急性脑分水岭梗死,疗效确切,安全可靠。
Objective To observe the efficacy of bermudagan and shenmai injection in the treatment of acute cerebral watershed infarction. Methods Forty-eight patients with acute cerebral infarction were randomly divided into treatment group and control group. Both groups were treated with citicoline or brain protein hydrolyzate, and the patients were given hypotensive blood pressure according to their blood pressure. Blood volume and cerebrovascular secondary prevention and treatment. The treatment group, the application of wave dimension 75mg, orally, once daily; Shenmai injection 50ml saline 250ml, intravenous infusion, once daily. In the control group, bevacizumab 75mg was given orally once daily. Both groups were 7d for a course of treatment. Results The total effective rate and markedly effective rate in the treatment group were 92.3% and 75%, respectively. The total effective rate and markedly effective rate in the control group were 80% and 60% respectively. There was significant difference between the two groups (χ2 = 16.372, P <0.01). Conclusion The combination of bermudagrass and shenmai injection in the treatment of acute brain watershed infarction has definite curative effect and is safe and reliable.