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本文观察了氟中毒大鼠血清皮质酮含量变化。发现在不同的实验条件下,氟中毒大鼠血清皮质酮含量均明显降低。认为在氟,糖皮质激素以及骨和胶原代谢之间一定存在某种联系,而这种联系可能在氟中毒的发病机制中占重要地位。
In this paper, we observed the changes of serum corticosterone in rats with fluorosis. It was found that under different experimental conditions, serum corticosterone levels were significantly decreased in rats with fluorosis. There is a certain link between fluoride, glucocorticoids, and the metabolism of bone and collagen, which may play an important role in the pathogenesis of fluorosis.