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【目的】研究新生儿败血症患儿血清白介素-6(IL-6)和C-反应蛋白(C-reactive protein,CRP)变化及临床意义。【方法】测定新生儿败血症组治疗前后及对照组血清IL-6和CRP值,比较相互间差异。【结果】败血症组血清IL-6和CRP明显高于对照组,治疗前明显高于治疗后。【结论】血清IL-6、CRP可作为新生儿败血症早期诊断依据。
【Objective】 To investigate the changes and clinical significance of serum interleukin-6 (IL-6) and C-reactive protein (CRP) in neonates with sepsis. 【Methods】 The serum IL-6 and CRP levels in neonatal sepsis group before and after treatment and control group were measured and compared with each other. 【Results】 The levels of serum IL-6 and CRP in sepsis group were significantly higher than those in control group before treatment, which were significantly higher than those before treatment. 【Conclusion】 Serum IL-6 and CRP can be used as the basis for early diagnosis of neonatal sepsis.