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目的:研究固定式左炔诺孕酮(LNG)宫内缓释剂对大子宫腺肌症的临床疗效。方法:对30例已确诊为子宫腺肌症的妇女放置固定式LNG宫内缓释剂,随访18个月,观察脱环率、带器妊娠率,比较痛经程度、月经量、血红蛋白水平及子宫大小变化情况。结果:配戴患者无脱环和带器妊娠发生,痛经程度明显缓解(P<0.05),月经量减少(P<0.05),血红蛋白水平显著提高(P<0.05),子宫体积呈缩小趋势(P<0.05)。结论:大子宫腺肌症患者放置固定式LNG宫内缓释剂,不易下移脱落,在避孕、缓解痛经及减少经量方面疗效显著,有较好的临床应用价值。
Objective: To study the clinical efficacy of intrauterine sustained release levonorgestrel (LNG) in large adenomyosis. Methods: Thirty patients with diagnosed as adenomyosis were treated with intrauterine sustained release of LNG, and were followed up for 18 months. The rate of decortication, pregnancy rate of the device, degree of dysmenorrhea, menstrual flow, hemoglobin and uterus Size changes. Results: Dysmenorrhea was significantly relieved (P <0.05), menstruation was reduced (P <0.05), hemoglobin level was significantly increased (P <0.05) and uterine volume was decreased (P <0.05). CONCLUSIONS: Large adenosine myopathy patients have fixed LNG intrauterine sustained-release agents, which are not easy to move down and fall off. They are effective in contraception, relieving dysmenorrhea and reducing the amount of menstruation, and have good clinical value.