患者,男,32岁。其妻29岁,结婚3年,共孕4次,除第1次为人工流产外,其余3次均在妊娠2月内自然流产。于1989年3月来我院就诊。孕期无患病史,无不良物质接触史。夫妇表型正常,身体健康。非近亲结婚。细胞遗传学检查取夫妇外周血淋巴细胞培养72小时后,常规方法制片,G显带,镜下分析60个中期分裂相,患者核型均为46,XY,t(18;20)(18qter→18p11::20p11→20pter;20qter→20p11::18p11→18pter)(附图)。其妻染色体核型正常。 Patient, male, 32 years old. His wife is 29 years old, married for 3 years, a total of 4 pregnancies, in addition to the 1st for abortion, the remaining three were in spontaneous abortion in February of pregnancy. In March 1989 to our hospital. No history of pregnancy during pregnancy, no adverse drug exposure history. The couple phenotype normal, in good health. Non-relatives get married. Cytogenetic analysis of peripheral blood lymphocytes from couples to 72 hours after culture, the conventional method of preparation, G band, microscopic analysis of 60 metaphase, karyotype patients were 46, XY, t (18q20 → 18p11 :: 20p11 → 20pter; 20qter → 20p11 :: 18p11 → 18pter) (with photos). His wife karyotype normal.