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目的了解本院抗菌药物的使用情况,为临床合理用药提供参考。方法采用金额排序法和用药频度(DDDs)排序法对医院2011年抗菌药物应用情况进行回顾性分析。结果 2011年医院抗菌药物销售额占全部药品销售额的18.06%;抗菌药品销售金额排在前3位的药品为头孢菌素类、氟喹诺酮类、β-内酰胺及β-内酰胺抑制剂类药物,其金额构成比分别为37.04%、13.63%和12.88%;抗菌药物DDDs排在前3位的为头孢菌素类、氟喹诺酮类和硝基咪唑类;头孢菌素中,第三代头孢菌素用药金额最高,第二代头孢菌素DDDs最大。结论本院抗菌药物用药结构比较稳定,但仍存在一些隐患,应加强抗菌药物的临床应用管理,同时强化临床微生物检测与细菌耐药性监测工作。
Objective To understand the use of antibacterials in our hospital and provide references for clinical rational use of drugs. Methods A retrospective analysis was conducted on the use of antibacterials in hospitals in 2011 by the method of ranking by amount and frequency of drug use (DDDs). Results In 2011, the sales volume of antimicrobial drugs in hospitals accounted for 18.06% of the total sales volume of drugs. The top three drugs with antibacterial sales were cephalosporins, fluoroquinolones, β-lactams and β-lactam inhibitors The amount of drugs accounted for 37.04%, 13.63% and 12.88%, respectively. Among the top three antibacterial drugs, DDDs were cephalosporins, fluoroquinolones and nitroimidazoles. In cephalosporins, the third generation cephalosporins The highest amount of mycotoxins, the second generation cephalosporins DDDs largest. Conclusion The antibacterial drug administration structure in our hospital is relatively stable, but there are still some hidden dangers. The clinical application of antibacterial drugs should be strengthened, and clinical microbiological tests and bacterial drug resistance monitoring should be strengthened.