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目的探讨超敏C-反应蛋白(High sensitive C-reactive protein,hs-CRP)、血尿酸(Uric acid,UA)与急性脑梗死的相关性。方法对急性脑梗死组30例,及对照组30例,进行超敏C-反应蛋白和血尿酸检测。结果急性脑梗死组患者hs-CRP、UA明显高于对照组,两组比较差异有统计学意义(P<0.05)。脑梗死组神经功能缺损轻、中、重型患者的UA浓度组间比较差异无统计学意义(P>0.05),中、重型患者的hs-CRP浓度分别与轻型组间比较差异有统计学意义(P<0.05)。结论 hs-CRP与缺血性脑血管病的发生和神经功能缺损程度相关,UA与缺血性脑血管病的发生有关而与神经功能缺损程度无关。
Objective To investigate the correlation between high sensitive C-reactive protein (hs-CRP), Uric acid (UA) and acute cerebral infarction. Methods 30 cases of acute cerebral infarction group and 30 cases of control group, high-sensitivity C-reactive protein and serum uric acid were detected. Results The hs-CRP and UA levels in patients with acute cerebral infarction were significantly higher than those in control group, with significant difference between the two groups (P <0.05). There was no significant difference in the concentration of UA among mild, moderate and severe patients with neurological deficit in cerebral infarction group (P> 0.05). The hs-CRP concentrations in moderate and severe patients were significantly different from those in mild group P <0.05). Conclusions hs-CRP is associated with the occurrence of ischemic cerebrovascular disease and the degree of neurological deficit. UA is associated with the occurrence of ischemic cerebrovascular disease but not with the degree of neurological deficit.