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目的 了解糖尿病肾病(DN)与视网膜病变(DR) 的关系。方法 对110 例Ⅱ型糖尿病患者进行12 h 尿白蛋白排泄率(UAER) 测定及眼底检查。结果 微量白蛋白尿发生率为36-4% ,DR 发生率为27-3% ,UAER升高组DR发生率较UAER正常组明显增高,分别为65-0% 和5-7% ,差异有显著性(P< 0-01)。DR发生率随病程增加及血糖的增高而增多。结论 DN的严重程度与DR 病变程度相符,二者均与病程、血糖控制及蛋白尿的水平有密切关系,糖尿病患者定期检查眼底及UAER对糖尿病微血管病变的早期诊治有重要意义。
Objective To understand the relationship between diabetic nephropathy (DN) and retinopathy (DR). Methods A total of 110 patients with type 2 diabetes mellitus underwent urinary albumin excretion rate (UAER) at 12 hours and fundus examination. Results The incidence of microalbuminuria was 36-4% and the incidence of DR was 27-3%. The incidence of DR in UAER elevated group was significantly higher than that in UAER normal group (65-0% and 5-7%, respectively) Significance (P <0-01). The incidence of DR increased with the course of disease and increased blood glucose. Conclusions The severity of DN is consistent with the severity of DR. Both of them are closely related to the course of disease, blood glucose control and the level of proteinuria. It is of great significance for diabetic patients to regularly examine the fundus and UAER for the early diagnosis and treatment of diabetic microangiopathy.