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【化学名】内消旋3,4-双(对溴乙酰氧基苯基)己烷。【结构式】【作用特点】本品为我国自行设计的己烷雌酚衍生物。对动物肿瘤 S_(180)、S_(37)的抑制率达60%左右。本品~(14)C 标化物给小鼠灌胃,30分钟可达血液中,3小时后达到高峰,维持12小时左右。~(14)C 标记化合物在带瘤小鼠组织中的分布以胃、肝、肾及肠中较高,其次是脾及骨骼等处。48小时后,70%自尿和粪便中排出。本品胃肠道吸收,作用较快,且副作用小,对造血系统无损伤作用。尚有提
[Chemical name] meso 3,4-bis (p-bromoacetoxyphenyl) hexane. 【Structure】 【Features】 This product is designed for our own hexane estrogen derivatives. On animal tumors S_ (180), S_ (37) inhibition rate of about 60%. This product ~ (14) C standardization of mice fed gavage, 30 minutes up to the blood, reached the peak after 3 hours, to maintain about 12 hours. The distribution of ~ (14) C-labeled compounds in the tumor-bearing mice tissues was higher in stomach, liver, kidney and intestine, followed by spleen and bone. After 48 hours, 70% of the urine and excrement were excreted. This product gastrointestinal absorption, the role of faster, and the side effects of small, no damage to the hematopoietic system. Still mention