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目的:评价胞必佳( N C W S) 联合全身化疗及单纯全身化疗对恶性胸腔积液的治疗作用。方法:75 例恶性胸腔积液患者随机分为联合组( 胞必佳胸腔内注射加全身化疗) 及单用全身化疗组两组。结果:联合组的有效率为91 .9 % ,优于单用全身化疗组的有效率57 .9 % ( P< 0 .01) 。结论:胞必佳胸腔内注射联合全身化疗优于单纯化疗控制胸水的疗效,值得临床推广应用。
Objective: To evaluate the therapeutic effects of N-CWS combined with systemic chemotherapy and systemic chemotherapy on malignant pleural effusion. METHODS: Seventy-five patients with malignant pleural effusion were randomly divided into two groups: the combination group (Pipide plus intrapleural injection plus systemic chemotherapy) and the systemic chemotherapy alone group. Results: The effective rate of the combined group was 91. 9 %, better than the effective rate of chemotherapy alone. 9 % (P< 0 .01). Conclusion: The combination of intravitreous injection with cell therapy and systemic chemotherapy is superior to chemotherapy alone in controlling pleural effusion. It is worthy of clinical application.