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目的:探索米非司酮合并米索前列醇(米索)终止6~16周妊娠的治疗效果。方法:将来自我院的160例孕6~16周要求终止妊娠的妇女,按孕周分成2种不同的治疗组。A组:100例,米非司酮25mg,每天2次,连服3天(总量150mg),第3天晨口服米索0.6mg,;B组:60例,米非司酮50mg每天2次,连服3天(总量300mg),第3天晨口服米索0.6mg,无效者,4小时后加服0.6mg。结果:A组24h内的流产成功率分别为95%。B组的成功率88.3%。结论:口服米非司酮配伍米索是终止6~16周妊娠的有效方法,可推荐临床应用。
Objective: To explore the therapeutic effect of mifepristone combined with misoprostol (misoprostol) to terminate the pregnancy of 6 to 16 weeks. METHODS: A total of 160 women from our hospital who requested termination of pregnancy for 6-16 weeks were divided into 2 different treatment groups according to gestational age. A group: 100 cases, mifepristone 25mg, 2 times a day, and even served 3 days (total 150mg), the first 3 days morning oral misoprostol 0.6mg, B group: 60 cases, mifepristone 50mg daily 2 Times, and even for 3 days (total 300mg), the first 3 days morning oral misoprostol 0.6mg, ineffective, add 0.6mg after 4 hours. Results: The success rate of miscarriage in group A within 24 hours was 95%. The success rate of group B was 88.3%. Conclusion: Oral mifepristone combined with misoprostol is an effective method to terminate the pregnancy of 6 ~ 16 weeks, which can be recommended for clinical application.