我院曾用静脉注射地塞米松逆转二例狼疮性肾炎并严重肾功衰竭,现报告如下。 1.患者(病案号67628)罗某,女性,20岁,广东人,因全身浮肿二个月伴恶心、呕吐一个月于1983年4月23日入院。入院前二个月,出现面部及下肢浮肿,尿少,食欲不振,在当地医院诊为“急性肾炎”,经输液、利尿等治疗未见好转,且逐日加重,日尿量减少为200～300ml。 颜面潮红,眼睑红肿,鼻旁两侧皮肤呈现蝶形红斑,双上肢及腕部,双下肢皮肤可见散在斑丘诊,双下肢轻度浮肿。白细胞7200/mm~3,中性杆状3％、分叶75%、淋巴18%、 Our hospital had used intravenous dexamethasone reversed two cases of lupus nephritis and severe renal failure, are as follows. 1 patient (case number 67628) Luomou, female, 20 years old, Cantonese, due to systemic edema two months with nausea, vomiting a month on April 23, 1983 admission. Two months before admission, his face and lower extremity edema, oliguria and loss of appetite appear. In the local hospital, he was diagnosed as “acute nephritis”. After transfusion and diuretic treatment, he did not see any improvement, and the daily urine output was reduced to 200-300ml . Face flushing, swelling of the eyelids, nasal papillary erythema on both sides of the skin appear, both upper extremities and wrists, both lower extremity skin scattered patchouan visible, mild edema of both lower extremities. White blood cells 7200 / mm ~ 3, 3% neutral rod, leaf 75%, lymph 18%