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目的:探讨阿奇霉素用于治疗小儿支原体肺炎患者中性粒细胞(NE)VCS参数的影响。方法:选取2008年9月—2013年3月期间确诊治疗的支原体肺炎患儿58例作为支原体治疗组,同期选取健康儿童10例作为健康对照组,采用Coulter LH-750型全自动分析仪对所有受试者的外周血进行白细胞计数(WBC)、NE的VCS参数测定分析。结果:支原体治疗组患者WBC、NEV、NEC、NDW数值明显高于健康对照组;NES数值明显低于健康对照组(P<0.05);治疗前支原体治疗组WBC、NEV、NEC、NDW数值明显高于治疗后,NES数值明显低于治疗后(P<0.05)。结论:小儿支原体肺炎患者中性粒细胞VCS参数的测定对其诊断具有重要的预测价值,病情好转时,WBC、NEV、NEC、NDW数值下降,NES数值上升,反之则疾病复发。
Objective: To investigate the effect of azithromycin on neutrophil (VCV) parameters in children with mycoplasma pneumonia. Methods: Fifty-eight mycoplasma pneumonia patients diagnosed and treated during September 2008-March 2013 were selected as mycoplasma treatment group. Ten healthy children were selected as healthy control group in the same period. Coulter LH-750 automatic analyzer Peripheral blood of the subject was measured for white blood cell count (WBC) and NE for VCS parameters. Results: The values of WBC, NEV, NEC and NDW in patients with mycoplasma were significantly higher than those in healthy controls (P <0.05). The values of NES and NDW in patients with mycoplasma were significantly higher After treatment, NES was significantly lower than after treatment (P <0.05). Conclusion: The determination of neutrophil VCS parameters in children with mycoplasma pneumonia is of great value in the diagnosis. When the condition is improved, the values of WBC, NEV, NEC and NDW are decreased and the NES value is increased, otherwise the disease recurred.