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目的观察胰岛素联合二甲双胍治疗2型糖尿病患者的临床疗效。方法将2型糖尿病患者68人,随机分成两组,每组34人,治疗组在胰岛素治疗基础上加用二甲双胍口服降糖药,对照组单纯使用胰岛素治疗。观察患者的血糖达标情况。结果治疗组空腹血糖达标率88.2%,餐后2h达标率82.5%,对照组空腹血糖达标率61.7%,餐后2h血糖达标率52.9%,两组患者其血糖达标率差异有统计学意义(P<0.05)。结论 2型糖尿病使用胰岛素治疗的患者在没有禁忌证的情况下,加用二甲双胍口服降糖药,临床疗效更佳。
Objective To observe the clinical efficacy of insulin plus metformin in type 2 diabetic patients. Methods 68 patients with type 2 diabetes mellitus were randomly divided into two groups with 34 patients in each group. The treatment group was given metformin oral hypoglycemic agents on the basis of insulin therapy, and the control group was treated with insulin alone. Observe the patient’s blood glucose compliance. Results In the treatment group, the fasting blood glucose level was 88.2%, the fasting blood glucose level was 82.5% in the control group, the fasting blood glucose level was 61.7% and the fasting blood glucose level was 52.9% in the control group. There was significant difference between the two groups (P <0.05). Conclusions Patients with type 2 diabetes using insulin therapy with metformin plus oral hypoglycemic agents in the absence of contraindications have better clinical outcomes.