骨髓增生异常综合征(MDS)是一组具有造血干细胞异质性的克隆性疾病,伴有血细胞质和量异常。其特点为主要发生在老年人,男性多于女性;外周血一系或三系血细胞减少,常为全血细胞减少;骨髓造血细胞有病态造血,2 0 %～4 0 %转化为急性白血病,是较为完整逐渐成癌的疾病模型。原发性M Myelodysplastic syndrome (MDS) is a group of clonal diseases with hematopoietic stem cell heterogeneity associated with abnormal cytoplasmic and cytoplasmic blood. Its characteristics are mainly in the elderly, more men than women; peripheral blood, one or three series of cytopenias, often pancytopenia; bone marrow hematopoietic hematopoietic cells, 20% ~ 40% into acute leukemia, is A more complete and gradually into cancer of the disease model. Primary M