慢性乙型病毒性肝炎(CBH)是我国多发、常见病,是肝硬化、肝细胞癌的最主要原因。其发病机制复杂,目前仍缺乏理想的治疗方法。干扰素因具有抑制和清除乙型肝炎病毒(HBV),减轻肝脏炎症,阻断肝脏纤维化的发生和发展,亦可防止肝细胞癌发生的作用而被广泛应用于CBH的治疗。然而普通 Chronic hepatitis B (CBH) is a frequent and common disease in our country. It is the most important cause of cirrhosis and hepatocellular carcinoma. The pathogenesis is complex, the current lack of ideal treatment. Interferon is widely used in the treatment of CBH because it can inhibit and eliminate hepatitis B virus (HBV), reduce liver inflammation, block the occurrence and development of liver fibrosis and prevent the occurrence of hepatocellular carcinoma. However normal