论文部分内容阅读
目的分析宫颈癌及癌前病变的相关危险因素。方法选取2010年12月至2013年12月间收治的宫颈上皮瘤样变和宫颈癌患者1 876例,其中宫颈上皮内瘤样变Ⅰ级、Ⅱ级、Ⅲ级和宫颈癌患者分别为776例、401例、482例和217例。另选取同期接受健康检查的育龄期妇女1239例作为对照组,对其进行阴道镜检查并病理检查证实未出现宫颈上皮瘤样变,调查并分析两组人群的临床资料。结果与对照组相比,宫颈上皮内瘤样变Ⅰ级、Ⅱ级与HPV感染、生产次数、文化程度、户籍等相关。宫颈上皮瘤样变Ⅲ级和宫颈癌与HPV感染、生产次数、初次性生活年龄、户籍、性生活年限等相关。结论宫颈癌的发生发展与HPV感染、初次性生活年龄及生产次数等相关,临床工作者在宫颈癌防治工作中应将其作为重点,加强宣教及随访管理。
Objective To analyze the related risk factors of cervical cancer and precancerous lesions. Methods A total of 1876 cases of cervical epithelial neoplasia and cervical cancer from December 2010 to December 2013 were selected. Among them, 776 cases of cervical intraepithelial neoplasia grade Ⅰ, Ⅱ, Ⅲ and cervical cancer, , 401 cases, 482 cases and 217 cases. Another 1290 women of childbearing age were enrolled in the same period as the control group. Colposcopy and pathological examinations were performed to confirm that no cervical epithelioid neoplasia was found. The clinical data of two groups were investigated and analyzed. Results Compared with the control group, cervical intraepithelial neoplasia grade Ⅰ, Ⅱ and HPV infection, the number of production, educational level, household registration and other related. Cervical epithelial neoplasia grade Ⅲ and cervical cancer and HPV infection, the number of production, the first sex life, household registration, sexual life and other related. Conclusions The occurrence and development of cervical cancer are related to HPV infection, the age of primary sexual life and the frequency of production. Clinicians should focus their efforts on the prevention and treatment of cervical cancer and strengthen their mission and follow-up management.