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目的 探讨重症监护病房(ICU)医院感染危险因素,制定防控策略.方法 对2015年1-6月入住ICU的132例患者进行目标性监测,并对医院感染危险因素进行多元回归分析.结果 共监测医院感染病例18例、24例次,医院感染发生率和例次发生率分别为13.64％和18.18％.医院感染部位以下呼吸道为主,占79.19％,其中呼吸机相关性肺炎占70.83％;医院感染病原菌以铜绿假单胞菌和鲍曼不动杆菌为主,占61％;高龄、侵入性操作、基础疾病和长时间住院是ICU医院感染发生的危险因素.结论 缩短患者ICU住院时间、加强高危患者管理是防控ICU医院感染发生的重要环节.“,”Objective To explore the risk factors of nosocomial infection in ICU,and to provide evidence for reducing the incidence of nosocomial infection.Methods 132 patients admitted from January to June to ICU in 2015 were targeted for surveillance,and the risk factors of nosocomial infection were analyzed by multiple regression analysis.Results 132 cases of ICU patients who were hospitalized for hospital infection were 18 cases and 24 case/times.The incidence rate of nosocomial infection and the incidence of cases was 13.64％,18.18％ respectively.The hospital infection in lower respiratory tract infection was on the top which accounted for 79.19％ (including ventilator-associated pneumonia pneumonia infection accounted for 70.83％);Pseudomonas aeruginosa and Acinetobacter Bauman were the main pathogenic strains of nosocomial infection that accounted for 61％.Age,invasive operation,basic disease and long time hospitalization were high risk factors of hospital infection in ICU.Conclusion Reducing the hospitalization time of patients in ICU and strengthening the four kinds of risk factors management are the key link of hospital infections in ICU for prevention and control.