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近一个多世纪以来,学者们一直在进行实验,试图用免疫学方法进行避孕。免疫避孕的优点是期望通过调动机体自身机能以达到较长期的避孕效果。从理论上讲此法是可逆的。至1960年大约已发表了150多篇关于动物及人类免疫避孕实验方面的文章。本文仅将抗人绒毛膜促性腺激素(hCG)抗体免疫避孕的研究综述如下: 一、hCG结构、作用及抗hCG免疫 hCG是由受精卵滋养层细胞所分泌的分子量为45,000~50,000道尔顿的糖蛋白;由α和β两个亚单位组成。对于hCG开始分泌的时间还有争议。用放射受体法及子宫内装
For more than a century, scholars have been experimenting, trying to contraceptive use of immunological methods. The advantage of immunocontraception is that it is expected to achieve a longer-term contraceptive effect by mobilizing the body’s own functions. In theory, this method is reversible. By 1960 about 150 articles on immunization contraception in animals and humans had been published. This article only anti-human chorionic gonadotropin (hCG) antibody immunocontraceptive research summarized as follows: First, the hCG structure, role and anti-hCG immunity hCG from the fertilized egg trophoblast cells secreted molecular weight 45,000 ~ 50,000 Dalton Of the glycoprotein; by α and β two subunits. The timing of the start of hCG secretion is still debatable. Radiation receptor method and the uterus inside