糖尿病的免疫学研究办法的成果主要是近十多年来取得的。按照现代的糖尿病分型,这些成果来自于1型糖尿病(即胰岛素依赖型糖尿病)。人们很早就认识了糖尿病与器官特异自身免疫病的临床联系,以后又发现糖尿病病人血清中,器官特异性自身抗体的阳性率增加。七十年代开始,现代的免疫学研究方法应用于本病的研究。一九七四年末,Bottazzo等 The results of the immunological research methods of diabetes are mainly obtained in the past decade or so. According to modern diabetes typing, these results come from type 1 diabetes (ie, insulin-dependent diabetes mellitus). People have long recognized the clinical relationship between diabetes and organ-specific autoimmune diseases, and later found that the serum of patients with diabetes, organ-specific autoantibodies increased the positive rate. Seventies, modern immunology research methods applied to the study of this disease. In late 1974, Bottazzo et al