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15-甲基前列腺素F_(2α)(简称15-甲基PGF_(2α))是一种人工合成的前列腺素同类物,作用强度是PGF_(2α)的10～20倍,对于子宫的作用远超过胃肠道,是一种高效的人工流产药物。我国在1974年合成了dl-15-甲基PGF_(2α),并用于中期妊娠引产获得成功。15-甲基PGF_(2α)的给药方法主要有三种:(1)官腔内和羊膜腔内注射,用药物的醇溶液加生理盐水稀释,或加高分子右旋醣酐或甲基羟乙基纤维素稀释,一次注射。(2)肌
15-Methyl prostaglandin F 2α (abbreviated as 15-methyl PGF 2α) is a synthetic prostaglandin congener with an action intensity of 10 to 20 times that of PGF 2α and its effect on the uterus far Beyond the gastrointestinal tract, is an efficient drug for abortion. China in 1974 synthesis of dl-15-methyl PGF_ (2α), and for the second trimester of labor induction of labor success. There are three main ways of administration of 15-methyl PGF_ (2α): (1) intra-articular and amniotic injection, with the drug solution diluted with saline, or add polymer dextran or methyl hydroxyethyl Cellulose dilution, one injection. (2) muscle