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棉酚是从棉籽或棉根提取出来的一种黄色化合物.1971年我国医药工作者发现棉酚有抑制雄性大鼠生育能力的作用.1972年以后,各地展开了大协作,现在全国已有十三个省、市和单位协作,对棉酚进行系统的研究.动物实验说明,棉酚能破坏睾丸曲精细管中的精子、精子细胞和精母细胞,从而破坏精于的发生过程,使精液中缺乏精子,达到抑制生育的能力.经过短期给药,停药后动物的生育能力可以恢复.还在小鼠、大鼠、豚鼠、兔、猫、狗和猴等实验动物进行了毒性观察,除狗对棉酚的毒性比较敏感外,对其他实
Gossypol is a yellow compound extracted from cottonseed or cotton root .In 1971, Chinese medical workers found that gossypol can inhibit the fertility of male rats .After 1972, a great deal of cooperation has taken place around the country, and now there are ten Three provinces, municipalities and units cooperate to systematically study gossypol.Animal experiments show that gossypol can destroy spermatozoa, spermatids and spermatocytes in testicular seminiferous tubules, thus undermining the process of sperm production, In the absence of sperm, to inhibit the ability to reproduce.After short-term administration, withdrawal of animals after fertility can be restored.Also in mice, rats, guinea pigs, rabbits, cats, dogs and monkeys and other experimental animals were observed toxicity, In addition to the dog’s toxicity to gossypol more sensitive to other real