动物实验表明腺苷鞘内用药可以改善顽固性神经性疼痛 ,其原理可能是激活脊髓腺苷A1受体活性。临床实验研究表明腺苷静脉与鞘内用药均可以改善疼痛症状 ,但腺苷鞘内用药对顽固性神经性疼痛的治疗很少有报道。为此本研究探讨了腺苷鞘内用药对顽固性神经性疼痛的疗效情况。1　资 Animal experiments show that intrathecal adenosine medication can improve refractory neuropathic pain, the principle may be activation of spinal adenosine A1 receptor activity. Clinical experimental studies have shown that adenosine intravenous and intrathecal administration can improve the pain symptoms, but adenosine intrathecal drug treatment of intractable neuropathic pain rarely reported. To this end, this study explored the efficacy of intrathecal adenosine intractable neuropathic pain. 1 capital