超高分辨率光学相干断层扫描仪在非渗出性年龄相关性黄斑变性病变中的应用

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:lin901102
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: To describe the appearance of the non-exudative forms of age related macular degeneration (AMD) as imaged by ultrahigh resolution optical coherence tomography (UHR-OCT). Methods: A UHR-OCT ophthalmic imaging system, which utilises a femtosecond laser light source capable of approximately 3 μm axial resolution, was employed to obtain retinal cross sectional images of patients with non-exudative AMD. Observational studies of the resulting retinal images were performed. Results: 52 eyes of 42 patients with the clinical diagnosis of non-exudative AMD were imaged using the UHR-OCT system. 47 of the 52 (90%) eyes had the clinical diagnosis of drusen and/or retinal pigment epithelial (RPE) changes. In these patients, three patterns of drusen were apparent on UHR-OCT: (1) distinct RPE excrescences, (2) a saw toothed pattern of the RPE, and (3) nodular drusen. On UHR-OCT, three eyes (6%) with a clinical diagnosis of non-exudative AMD had evidence of fluid under the retina or RPE. Two of these three patients had findings suspicious for subclinical choroidal neovascularisation on UHR-OCT. Conclusion: With the increased resolution of UHR-OCT compared to standard OCT, the involvement of the outer retinal layers are more clearly defined. UHR-OCT may allow for the detection of early exudative changes not visible clinically or by angiography. Aim: To describe the appearance of the non-exudative forms of age related macular degeneration (AMD) as imaged by ultrahigh resolution optical coherence tomography (UHR-OCT). Methods: A UHR-OCT ophthalmic imaging system, which utilizations a femtosecond laser light source capable of approximately 3 μm axial resolution, was employed to obtain retinal cross sectional images of patients with non-exudative AMD. Observational studies of the resulting retinal images were performed. Results: 52 eyes of 42 patients with the clinical diagnosis of non-exudative Of these patients, the three patterns of drusen were apparent on UHR-OCT : (1) distinct RPE excrescences, (2) a saw toothed pattern of the RPE, and (3) nodular drusen. On UHR-OCT, three eyes (6%) with a clinical diagnosis of non-exudative AMD had evidence of fluid under the retina or RPE. Two of t hese three patients had findings suspicious for subclinical choroidal neovascularisation on UHR-OCT. Conclusion: With the increased resolution of UHR-OCT compared to standard OCT, the involvement of the outer retinal layers are more defined. of early exudative changes not visible clinically or by angiography.
其他文献
是人总会长大,是车总会改款。与那些少年得志的人在成长过程中总会被人寄予厚望一样,被称为史上最美大众汽车的CC,那款诞生之日便囊括汽车设计顶级大奖的汽车,它的改款也同样
加入世贸组织 ,对于每个普通的中国人来说 ,都具有非凡的意义。这不仅仅意味着我们会买到更便宜的汽车 ,吃到美国的柑橘 ,加拿大的小麦 ,我们当中的一部分人会因国际新规则的
孩子上小学,最焦虑的是妈妈孩子从幼儿园过渡到小学,一下子进入一个陌生的小社会,一想到他们面对老师、同学,面对困难慌张得想哭的小脸,妈妈们就心疼。妈妈们都特别渴望孩子
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
铁道部第十三工程局中心医院是一所具有35年军龄、51年创业史、环境优雅、基础设施齐全的综合性医院。该医院1994年通过二级乙等医院评审,1996年通过国家爱婴医院评估,1994
一、小麦病虫害麦蚜大发生,发生面积3600万亩;小麦吸浆虫中等偏重发生,局部大发生,发生范围将进一步扩大,发生面积1200万亩;小麦白粉病、麦蜘蛛中等偏重发生,局部大发生;小麦
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
期刊
全面贯彻民主集中制,这是党中央提出的开展“三讲”教育四个基本要求之一,也是当前加强党的组织建设和领导班子建设需要着重解决的一个问题。医疗卫生单位的党政领导,有必要
确定燕窝唾液糖蛋白寡糖链由5种糖组分构成,它们具有特定的量比关系。据此建立的燕窝及其制品的气相色谱检测方法可同时完成定性鉴别和定量分析,具有特征性强,干扰少,简便可靠的特
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.