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头孢菌素类抗生素 ,尤其是第二、三代头孢菌素 ,因其使用后在体内分布广 ,杀菌力强 ,抗菌谱广 ,毒性低 ,血清浓度高 ,耐 β -内酰胺酶等优点 ,已被广泛应用于临床。肾衰竭患者在应用此类抗生素时 ,应根据其肌酐清除率 (Ｃｃｒ)酌情减少用量。近二年来 ,我院发现 10例慢性肾衰竭
Cephalosporin antibiotics, especially the second and third generation cephalosporins, have been widely used in the body after their use, they are widely bactericidal, have wide antibacterial spectrum, low toxicity, high serum concentration and resistance to β - lactamase. Is widely used in clinical. Patients with renal failure in the use of such antibiotics, should be based on its creatinine clearance (Ccr), as appropriate, reduce the amount. In the past two years, our hospital found 10 cases of chronic renal failure