目的:探讨研究奥美拉唑在胃溃疡出血中的治疗效果。方法:选取300例来我院治疗胃溃疡出血患者随机分为对照组和试验组,对照组给予雷尼替丁治疗,每次200mg加至100ml生理盐水中静脉滴注,每天2次;试验组给予奥美拉唑口服,一次20mg,每晨1次,连续治疗2个月后,比较两组临床效果。结果:对照组总有效率82%,试验组总有效率96%,差异具有统计学意义(P<0.05)。结论:奥美拉唑比传统的组胺H2受体拮抗剂临床效果更优,值得在临床推广。 Objective: To investigate the therapeutic effect of omeprazole in gastric ulcer bleeding. Methods: 300 cases of gastric ulcer bleeding in our hospital were randomly divided into control group and experimental group. The control group was treated with ranitidine, 200mg each time plus 100ml normal saline intravenously, twice a day. The experimental group Omeprazole given orally, once 20mg, every morning 1, continuous treatment 2 months later, the clinical effect of two groups were compared. Results: The total effective rate of the control group was 82%, the total effective rate of the experimental group was 96%, the difference was statistically significant (P <0.05). Conclusion: Omeprazole has better clinical effect than traditional histamine H2 receptor antagonists, which is worthy of clinical application.