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有临床资料显示 ,有癫病史或癫发作的患者脑脊液和血浆白细胞介素 6 (IL 6 )浓度升高 ,动物实验也证明 ,在各种癫发作模型中脑内IL 6表达增加。我们试图通过研究红藻氨酸 (KA)诱导癫发作的动物模型相关脑区中IL 6的表达特征及其与c Fos表达的比较 ,进一步探讨IL 6在癫?
Clinical data show that cerebrospinal fluid and plasma interleukin 6 (IL 6) levels are elevated in patients with a history of epilepsy or epileptic seizures. Animal studies have also demonstrated an increase in intracerebral IL 6 expression in various epileptic seizures. We attempted to further investigate the role of IL-6 in the pathogenesis of epilepsy by studying the expression of IL-6 in the relevant brain regions of kainic acid (KA) -induced epileptic seizures and its comparison with c Fos expression.