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目的:探讨动脉内中西药物灌注治疗对于老年性动脉硬化闭塞症患者的效果。方法:3例男性老年性动脉硬化患者,经对侧股动脉穿刺插管,灌注罂粟碱30mg,葛根素300mg,尿激酶40万单位,盐酸山莨菪碱10mg,川芎嗪240mg,上述药物用低分子右旋糖酐210ml和生理盐水210ml稀释后经导管缓慢注入。有下肢感染者注入抗生素。导管保留1周,期间灌注相同药物,1次/d。结果:1周后造影复查缺血下肢血供均有改善,溃疡愈合,避免了截肢。随访患侧下肢缺血症状消失,皮温恢复正常,疼痛消失,达到了临床痊愈。结论:动脉内中西药物灌注治疗对于老年性动脉硬化闭塞症患者是一种有效的方法。
Objective: To investigate the effect of intra-arterial infusion of Chinese and Western medicine on senile arteriosclerosis obliterans. Methods: Three male patients with senile arteriosclerosis were anesthetized by injecting 30mg papaverine, 300mg puerarin, 400000 units of urokinase, 10mg anisodamine hydrochloride and 240mg ligustrazine through the contralateral femoral artery. Dextran 210ml and 210ml normal saline diluted by catheter slowly injected. Infected with lower limb infection antibiotics. Catheter for 1 week, during the same drug infusion, 1 / d. Results: 1 week after angiography review ischemic lower limb blood supply have improved, ulcer healing, to avoid amputation. Follow-up ipsilateral lower limb ischemic symptoms disappeared, skin temperature returned to normal, the pain disappeared, reaching clinical recovery. Conclusion: Intra-arterial infusion of Chinese and Western drugs for senile arteriosclerosis obliterans patients is an effective method.