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目的：评估准分子激光原位角膜磨镶术（LASIK）治疗高度近视的安全性、有效性、稳定性及预测性。方法：采用SCMD气动式角膜切割刀及SCHWINDKERATOM－F型准分子激光系统，对高度近视[等值球镜-6．25D~-30．00D，平均（－12．50±5．39）D]104例164只眼行LASIK手术，其中屈光度-6．25D~－9.50D（A组）74只眼；屈光度-10．13D~－15．00D（B组）35只眼；屈光度-15．50D~-30．00D（组）55只眼。术后随访观察6个月以上。结果；术后自觉症状轻微，无角膜雾状混浊及眼压升高。术后6个月探眼视力≥1．0者A、B、C3组分别达73．0％、57．1％及7．3％，裸眼视力≥0．5者分别达100．0％、91．4％及50．9％；屈光度在±1．00D以内的分别达75．7％、45．7％及16．4％，在±3．00D以内的分别达1000％、91．4％及58．2％。99．4％术眼，术后1个月、3个月及6个月的最佳矫正视力与术前相比，未有低于2行以上者。结论：LASIK手术对于矫治高度近视有很好的疗效，无明显并发症，对于远期结果尚需进一步观察。
Objective: To evaluate the safety, efficacy, stability and predictive ability of laser in situ keratomileusis (LASIK) in the treatment of high myopia. Methods: Using SCMD pneumatic corneal cutting knife and SCHWINDKERATOM-F excimer laser system, high myopia [equivalent spherical -6.25D ~ -30.00D, average (-12.50 ± 5.39) D] One hundred and forty-four eyes (164 eyes) underwent LASIK. There were 74 eyes with diopter -6.25D ~ -9.50D (group A), 35 eyes with diopter -10.13D ~ -15.00D (group B), and diopter -15.50D ~ -30.00D (group) 55 eyes. Postoperative follow-up observation of 6 months or more. Results; minor symptoms after surgery, no corneal haze and intraocular pressure increased. The visual acuity ≥1.0 at 6 months after surgery was 73.0%, 57.1% and 7.3% in group A, B and C3, respectively. The visual acuity of the naked eye≥0.5 was 100.0% 91.4% and 50.9% respectively; within 75%, 45.7% and 16.4% of ± 1.00D, respectively, within ± 3.00D, respectively, up to 1000%, 91.4% % And 58.2% respectively. 99.4% of the eyes, 1 month after surgery, 3 months and 6 months best corrected visual acuity compared with preoperative, no less than 2 lines above. Conclusion: LASIK has a good curative effect in the treatment of high myopia without obvious complication, and the long-term results need to be further observed.