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生长于巴西东南部的沙氏番荔枝An-nona salzmanii D.C.常做为民间用药治疗肠虫病、痢疾、溃疡和一些炎症。本文将报道其树皮中所含有的四种苄基异喹啉生物碱:苄基四氢异喹啉-网状番荔枝碱(reticuline)及三种阿朴啡类生物碱,包括番荔枝碱(anon-ainc)劳瑞停(laurelliptine)和异波尔定(isoboldine)。在进行成分分离之前,需将干燥茎皮粉末的乙醇提取液过滤并减压浓缩,残留物经己烷和二氯甲烷洗后悬浮于Na_2CO_3水溶液中,进而以氯仿萃取,萃取层减压浓缩后通过
The An-nona salzmanii D.C., which grows in the southeast of Brazil, is often used as a folk medicine to treat helminths, dysentery, ulcers and some inflammation. This article will report the four benzyl isoquinoline alkaloids contained in its bark: benzyl tetrahydroisoquinoline-reticuline and three apomorphine alkaloids, including analgenine. (anon-ainc) laurelliptine and isoboldine. Before the separation of the components, the ethanol extract of the dry bark powder was filtered and concentrated under reduced pressure. The residue was washed with hexane and methylene chloride and suspended in an aqueous solution of Na 2 CO 3 , followed by extraction with chloroform, and the extract layer was concentrated under reduced pressure. by