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目的:评价iRoot SP在不同充填技术下充填根管的根尖微渗漏情况。方法:下颌单根前磨牙36颗，ProTaper Universial镍钛锉预备至F3，将处理好的样本随机分成4个实验组(每组n n＝8)、阴性对照组(n n＝2)和阳性对照组(n n＝2)。实验组分别为冷侧压技术组(CLC)(A组)；热牙胶技术组(CWC)(B组)；单尖法技术组(SC)(C组)；纯糊剂技术组(SOB)(D组)。将充填好的样本放入37 ℃恒温水浴箱内7 d，然后实验组样本除根尖1 mm外全部用指甲油封闭，阴性对照组全封闭，阳性对照组不涂指甲油。所有样本根尖均浸入0.1%亚甲蓝溶液7 d，然后在低速切片机上沿牙长轴纵向切开，在显微镜下(×10)观察并拍照记录，使用image J软件测算根尖渗漏的数值。n 结果:单尖法技术组根尖渗漏值最大(5.02±2.23)mm，热牙胶技术组最小(3.59±1.76)mm，纯糊剂技术组的根尖渗漏值小于单尖法技术，但四种充填技术之间差异无统计学意义(n P>0.05)。n 结论:所有充填技术都不能完全封闭根尖。iRoot SP纯糊剂技术具有与其他技术相似的根尖封闭性能。“,”Objective:The aim of this study was to evaluate different root canal obturation techniques on apical sealing ability of iRoot SP.Methods:Thirty-six single root mandibular premolar were collected. The root canals were mechanically instrumented with ProTaper rotary files to F3. The prepared samples were randomly divided into four experimental groups (n n=8) for root canal filling. The remaining four teeth were classified as a negative group (n n=2) and a positive control group (n n=2) respectively. The canals in the four experimental groups were obturated with gutta-percha and (or) iRoot SP, by either cold lateral compaction technique (CLC), continuous wave condensation technique (CWC), single-core technique (SC) or Sealer only backfill technique (SOB) respectively. The samples were then placed in a 37 ℃ water bath for 7 days to allow completely harden. All samples of experimental groups were sealed with nail polish except 1 mm from the apex and negative control group was fully enclosed while positive control group was fully open, then all root tips were immersed in 0.1% methylene blue solution for 7 days, then cut along the long axis of the tooth on a low-speed microtome, observed under a microscope (X10) and photographed. The software of image J was used to measure the apical leakage.n Results:Apical microleakage were present in all filling techniques. SC technology showed higher apical leakage [(5.02±2.23)mm], while CWC showed lower [(3.59±1.76)mm], but there were no statistical difference ( n P>0.05).n Conclusions:All filling techniques can not completely seal the root apical, SOB technology has the similar apical sealing performance as other techniques.