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病人,男,61岁。因胸闷、头晕,左腹部坠胀感2年入院。患病以来经常感烦躁,乏力,曾查红细胞7.6×10~(12)/L,血红蛋白175g/L,红细胞压积0.65.骨髓像示红系增生明显活跃,各期形态大致正常。骨髓诊断为真性红细胞增多症。治疗给予口服环磷酰胺200mg/d,用药1月余,因白细胞降至4.7×10~9/L后而停药,此后间断服用复方丹参片,未用其他治疗真性红细胞增多症药物。近来前述症状加重,查体:肝肋下2cm,剑突下4cm;脾肋下5cm,质韧,无触痛。血象:白细
Patient, male, 61 years old. Due to chest tightness, dizziness, left abdominal bulge 2 years admitted. Frequent irritability, fatigue since the onset of illness, had checked erythrocytes 7.6 × 10 ~ (12) / L, hemoglobin 175g / L, hematocrit 0.65. Bone marrow showed erythroid hyperplasia was significantly active, the various phases of the morphology is generally normal. Marrow diagnosis of polycythemia vera. Treatment was given oral cyclophosphamide 200mg / d, more than 1 month medication, due to white blood cells dropped to 4.7 × 10 ~ 9 / L after the withdrawal, then discontinuous taking compound Danshen tablets, no other treatment of polycythemia vera drugs. Recently the above symptoms worse, physical examination: liver ribs 2cm, xiphoid 4cm; Spleen ribs 5cm, quality tough, no tenderness. Blood: white