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百草枯中毒是基层医院的常见病,其临床死亡率极高。本研究从百草枯中毒的发病机制,临床表现做了简单的阐述。我国农村百草枯的应用非常普遍。百草枯为触灭生性除草剂,对人的毒性极高,中毒以后可引起消化道黏膜糜烂出血,肺纤维化形成,多脏器功能识衰竭。发病后因无特效解毒药,临床死亡率高达75%,是目前中毒后病死率最高的除草剂。本科自2006年1月至2008年12月收治百草枯中毒22例,常规治疗不变情况下,早期加用大剂量激素和持续血液灌流取得了较显著疗效。现总结报告如下。
Paraquat poisoning is a common disease in primary hospitals and its clinical mortality rate is extremely high. This study made a brief exposition of the pathogenesis and clinical manifestations of paraquat poisoning. The application of paraquat in our country is very common. Paraquat as a touch off biological herbicides, high toxicity to humans, can cause gastrointestinal mucosal bleeding after bleeding poisoning, pulmonary fibrosis, multiple organ failure. After the onset of non-effective antidote because of drugs, the clinical mortality rate as high as 75%, is currently the highest mortality after poisoning herbicides. Undergraduate from January 2006 to December 2008 admitted to paraquat poisoning in 22 cases of conventional treatment unchanged, early with high-dose hormone and continuous hemoperfusion achieved more significant effect. The report is summarized as follows.