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目的探讨昂丹司琼注射液配合中药敷脐治疗由顺铂(DDP)引起的恶心呕吐的临床疗效。方法将120例含DDP联合化疗的恶性肿瘤患者随机分成A、B 2组,A组予昂丹司琼注射液配合中药敷脐,B组仅予昂丹司琼。结果 A组对呕吐的有效控制率显著高于B组(P<0.05),且可有效保护患者生活质量。2组不良反应比较无明显差异。结论昂丹司琼注射液配合中药敷脐可以有效控制顺铂的联合化疗所致的恶心呕吐,并保护患者生活质量。
Objective To investigate the clinical efficacy of Ondansetron injection combined with Chinese herbal Umbilicus in the treatment of nausea and vomiting caused by cisplatin (DDP). Methods 120 patients with malignant tumor containing DDP combined with chemotherapy were randomly divided into A and B 2 groups. A group received Ondansetron injection combined with Umbilical cord blood application, while B group received only ondansetron. Results The effective control rate of vomiting in group A was significantly higher than that in group B (P <0.05), and it could effectively protect the quality of life of patients. No significant difference in adverse reactions between the two groups. Conclusion Ondansetron injection combined with Umbilicus can effectively control nausea and vomiting induced by cisplatin combined with chemotherapy and protect the quality of life of patients.